PROJECTS
   

Project
Acronym:  
Name: The effect of montelukast on cytokine secretion in children with bronchial asthma 
Project status: From: 2005-07-25 To: 2006-07-25 (Completed)
Type (Programme): BILAT 
Project funding: -
International partner
Organisation Name: Merck & Co., Inc. 
Organisation adress:  
Organisation country: Sjedinjene američke države 
Contact person name:  
Contact person email:  
Croatian partner
Organisation name: Medicinski fakultet 
Organisation address:  
Contact person name: Gagro, Alenka
Contact person tel:
  Contact person fax:  
Contact person e-mail: Email 
Short description of project
The purpose of this study is to define the effect of 4 week monotherapy with with an oral antagonistof cysteinyl leukotriene receptors (CysLT1) montelukast on the secretion of regulatory cytokines, IL-10 and TGF-beta, bronchial hyperresponsiveness and clinical parameters in atopic asthma children. The methods used will enable us to investigate which cell subset is a target for a possible effect of montelukast on the regulation of these immunoregulatory cytokines. 
Short description of the task performed by Croatian partner
 


   

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